There is more than one kind of B3, each having its own role in our body:
- Inositol hexanicotinate
As originally discovered by Dr. William Kaufman, M.D., Ph.D., in 1949, sufficient quantities of niacinamide completely controls osteoarthritis pain and swelling in most cases. (Niacinamide is a water-soluble form of B3, not to be confused with niacin, a different B3 form.)
In addition, Dr. Kaufman found that niacinamide can relieve both anxiety and depression — two conditions that are common in osteoarthritis patients.
From: Healing with nutrition
(My words) B6 speeds ip tryptophan breakdown, and niacinamide slows it down. This means that if you’re taking large amounts of B6, your tryptophan will be low. Taking niacinamide prevents this from happening.
Niacinamide can be hard on the liver. Your body will let you know by making you nauseous.
Inositol hexanicotinate is the B3 used in the iodine companions.